The vision of BioNEC is to revolutionize bottom-up nanoscale engineering by integrating state-of-the-art lipid, peptide and carbohydrate chemistry with nucleic acid based self-assembly.
We will design and synthesize building blocks for controlled assembly of unique and functional nanostructures in solution, on surfaces, and on cells.
Within BioNEC, the assembled nanostructures will be explored to solve concrete scientific challenges relating to synthetic chemistry and biological recognition processes.
The unique features of the planned research comprise several elements:
- We will make nanotechnology with great precision through our unique ability to chemically functionalize DNA/LNA duplexes with Ångström-scale accuracy;
- We will explore our efficacious and innovtive method for attachment of nucleic acids into liposomes in novel directions;
- We will integrate state-of-the-art lipid, peptide and carbohydrate chemistry with DNA-based self-assembly;
- We will study the chemical, structural and biological properties of the nanobio-systems.
The specific research projects of BioNEC include nano-synthesis, biomolecular catalysis, DNA-controlled synthesis of oligosaccharides and DNA-based de novo design and synthesis of proteins.
The innovative constellation and scientific synergism of BioNEC is expected to lead to breakthrough ideas and unique research results.