Christian has been a member of the Kim Ravnskjaer group since 2019, specializing in computational analysis of advanced genomics. His research has been focusing on immune cell involvement in rheumatoid arthritis, optimizing cell-type deconvolution algorithms for human metabolically associated steatohepatitis (MASH), and contributing to the COST Action program’s Mye-InfoBank project, which investigates molecular profiles of myeloid cells as biomarkers for inflammation and cancer. In this project, he has worked extensively with large-scale bulk RNA-seq data from inflammatory bowel disease (IBD). Additionally, he has conducted single-cell RNA sequencing analyses of MASH in adult mice to explore the function of HSC-expressed plasmalemma vesicle-associated protein (PLVAP).
In October 2024, Christian joined the ATLAS project as a PhD fellow, focusing on computational biology approaches to single/nuclei -cell and spatial transcriptomics. His research aims to map cellular interactions and liver tissue plasticity during the development and regression of steatohepatitis. Through the integration of single-cell and spatial omics data, he seeks to uncover new biological insights into liver disease.